Adipokine resistin predicts anti-inflammatory effect of glucocorticoids in asthma
نویسندگان
چکیده
منابع مشابه
Glucocorticoids: mechanisms of action and anti-inflammatory potential in asthma.
GLUCOCORTICOIDS are potent inhibitors of inflammatory processes and are widely used in the treatment of asthma. The anti-inflammatory effects are mediated either by direct binding of the glucocorticoid/glucocorticoid receptor complex to glucocorticoid responsive elements in the promoter region of genes, or by an interaction of this complex with other transcription factors, in particular activat...
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Airway inflammation is a central feature in the pathophysiology of asthma and cytokine networks play a fundamental role in the chronic inflammatory process. Anti-inflammatory treatment with inhaled corticosteroids provides the mainstay of asthma management in conjunction with bronchodilator therapy. Short-acting b2-adrenoceptor agonists have been used as bronchodilator treatment in asthma for d...
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Background: Recently many studies have focused on the possible role of corticosteroids inhalation on osteoporosis in asthma patients. This study aimed to determine whether the indicatives of bone formation or resorption are different between asthma patients with healthy subjects. Materials and Methods: To achieve this outcome, twenty one middle-aged asthma patients treated with inhaled cortico...
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Abstract Aims: To investigate the effect of Myrtenol, the active ingredient of Myrtle, on the oxidant and anti-oxidant indices and cytokines in the allergic asthma. Methods: Allergic asthma was induced by ovalbumin (OVA) sensitization and inhalation in four groups of rats; Control, Asthma, Asthma+Dexamethasone and Asthma+Myrtenol. Myrtenol (50mg/kg) or Dexamethasone (2.5mg/kg) was a...
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Escin is a natural mixture of triterpenoid asponin isolated from the seed of the horse chestnut and demonstrates anti-oedematous and anti-inflammatory effects. As yet, the precise mechanisms by which escin exerts its antiinflammatory effects remain unclear. The data from current studies indicate that the anti-inflammatory properties of escin were attributed to its ability to reduce the adhesive...
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ژورنال
عنوان ژورنال: Journal of Inflammation
سال: 2011
ISSN: 1476-9255
DOI: 10.1186/1476-9255-8-12